Download E-books Forward-Time Population Genetics Simulations: Methods, Implementation, and Applications PDF

Computer Simulation

By Bo Peng

The one publication on hand within the zone of forward-time inhabitants genetics simulations—applicable to either biomedical and evolutionary experiences

The fast raise of the facility of private desktops has ended in using severe forward-time simulation courses in genetic reports. Forward-Time inhabitants Genetics Simulations offers either new and universal tools, and introduces simuPOP, a robust and versatile new software that may be used to simulate arbitrary evolutionary tactics with targeted positive aspects like personalized chromosome forms, arbitrary nonrandom mating schemes, digital subpopulations, details fields, and Python operators.

The publication starts off with an summary of vital thoughts and versions, then is going directly to convey how simuPOP can simulate a couple of usual inhabitants genetics models—with the aim of demonstrating the impression of genetic components comparable to mutation, choice, and recombination on typical Wright-Fisher types. the remainder of the publication is dedicated to purposes of forward-time simulations in a variety of examine topics.

Forward-Time inhabitants Genetics Simulations includes:

  • An evaluation of at the moment on hand forward-time simulation equipment, their merits, and shortcomings

  • An evaluate and evaluate of at the moment on hand software

  • A simuPOP tutorial

  • Applications in inhabitants genetics

  • Applications in genetic epidemiology, statistical genetics, and mapping complicated human diseases

The merely e-book of its variety within the box at the present time, Forward-Time inhabitants Genetics Simulations will attract researchers and scholars of inhabitants and statistical genetics.

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