Download E-books Lampbrush Chromosomes (Molecular Biology, Biochemistry and Biophysics Molekularbiologie, Biochemie und Biophysik) PDF

Biochemistry

In 1965 i used to be requested by way of Dr. Konrad Springer even if i might ponder writing a monograph on "Lampbrush chromosomes and their physiological meaning", and even if I authorised in precept I refused to write down there after which, or to fulfill a time limit. i needed to proceed with my very own study, and that i had different tasks that left me with little loose time, yet a way more very important attention was once that during the Sixties the topic used to be beset by way of a number of unresolved questions. I felt that to put in writing a evaluate then will be untimely, jam-packed with speculations a lot of which might be refuted, and certainly have been refuted, in the subsequent decade or . Had I written at the moment the only virtue over the current could were that few biologists have been learning lampbrush chromo­ somes, and the printed literature was once for this reason scanty. i'm pleased that I insisted on hold up, and am thankful for Springer Verlag's sufferer reputation of my selection. the 1st bankruptcy of this monograph describes the background of study on lampbrush chromosomes from their discovery in the direction of the top of the nineteenth century till the early Nineteen Sixties. by way of then numerous evidence touching on their constitution and chemistry were firmly validated, together with the facts lampbrush chromatid is unineme; it encompasses a unmarried uninterrupted DNA duplex. This uncovered an immense challenge, the C-value paradox; grades of complexity of association in eukaryotes are unrelated to their genome sizes.

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